Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of SecA2-dependent substrates inMycobacterium marinumidentifies protein kinase G (PknG) as a virulence effector

12 Oct 2013

Abstract excerpt

The pathogenicity of mycobacteria is closely associated with their ability to export virulence factors. For this purpose, mycobacteria possess different protein secretion systems, including the accessory Sec translocation pathway, SecA2. Although this pathway is associated with intracellular survival and virulence, the SecA2-dependent effector proteins remain largely undefined. In this work, we studied a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Genetics and Biotechnology
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24119166
DOI: 10.1111/cmi.12221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of SecA2-dependent substrates inMycobacterium marinumidentifies protein kinase G (PknG) as a virulence effectorPMID 24119166Read ↗

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspFSemantic proximity Read ↗

PPE38 Modulates the Innate Immune Response and Is Required for Mycobacterium marinum VirulenceSemantic proximity Read ↗

The Accessory SecA2 System of Mycobacteria Requires ATP Binding and the Canonical SecA1.Semantic proximity Read ↗

The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulenceSemantic proximity Read ↗

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component.Semantic proximity Read ↗

Proteo-genetic analysis reveals clear hierarchy of ESX-1 secretion in Mycobacterium marinumSemantic proximity Read ↗

A Small Protein but with Diverse Roles: A Review of EsxA in Mycobacterium–Host InteractionSemantic proximity Read ↗

SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosisSemantic proximity Read ↗

The antagonistic transcription factors, EspM and EspN, regulate the ESX-1 secretion system in <i>M. marinum</i>Semantic proximity Read ↗

The antagonistic transcription factors, EspM and EspN, regulate the ESX-1 secretion system in M. marinumSemantic proximity Read ↗

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10Semantic proximity Read ↗

Protein export by the mycobacterial SecA2 system is determined by the preprotein mature domain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.