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Article

Identification of a second Listeria secA gene associated with protein secretion and the rough phenotype.

Molecular microbiology - 1 Aug 2002

Lenz Laurel L, Portnoy Daniel A

Abstract excerpt

We describe the identification and characterization of a second secA gene in Listeria monocytogenes. This gene, termed secA2, is involved in smooth-rough phenotypic variation and secA2 expression contributes to bacterial virulence. Spontaneous rough (R-) variants of L. monocytogenes grow in chains and form rough colonies on solid media. A subset of R-variants, classified here as type I, also shows reduced...

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Identifiers

PMID: 12180923
DOI: 10.1046/j.1365-2958.2002.03072.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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