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Article

Influence of the apolipoprotein E epsilon4 allele on human embryonic development.

Neuroscience letters - 24 May 2002

Zetterberg Henrik, Palmér Mona, Ricksten Anne, Poirier Judes, Palmqvist Lars, Rymo Lars, Zafiropoulos Alexander, Arvanitis Demetrios A, Spandidos Demetrios A, Blennow Kaj

Abstract excerpt

Human apolipoprotein E (apoE) exists in three major isoforms encoded by distinct alleles (APOE epsilon2, epsilon3 and epsilon4) and has important functions in nerve development and repair. Inheritance of the 4 allele is a major risk factor for the development of Alzheimer's disease. To investigate the role of APOE polymorphisms in embryonic development, we analyzed the APOE genotypes of 81 spontaneously aborted...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12009520
DOI: 10.1016/s0304-3940(02)00198-2

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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