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Article

APOE gene and neuropsychiatric disorders and endophenotypes: A comprehensive review.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2018

Forero Diego A, López-León Sandra, González-Giraldo Yeimy, Dries Daniel R, Pereira-Morales Angela J, Jiménez Karen M, Franco-Restrepo Juan E

Abstract excerpt

The Apolipoprotein E (APOE) gene is one of the main candidates in neuropsychiatric genetics, with hundreds of studies carried out in order to explore the possible role of polymorphisms in the APOE gene in a large number of neurological diseases, psychiatric disorders, and related endophenotypes. In the current article, we provide a comprehensive review of the structural and functional aspects of the APOE gene and...

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Source

Identifiers

PMID: 27943569
DOI: 10.1002/ajmg.b.32516

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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