Article
Crucial role of Bysl in mammalian preimplantation development as an integral factor for 40S ribosome biogenesis.
Molecular and cellular biology - 1 Mar 2007
Adachi Kenjiro, Soeta-Saneyoshi Chie, Sagara Hiroshi, Iwakura Yoichiro
Abstract excerpt
Blastocyst formation during mammalian preimplantation development is a unique developmental process that involves lineage segregation between the inner cell mass and the trophectoderm. To elucidate the molecular mechanisms underlying blastocyst formation, we have functionally screened a subset of preimplantation embryo-associated transcripts by using small interfering RNA (siRNA) and identified Bysl (bystin-like)...
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