Article
Initial virological response and viral mutation with adefovir dipivoxil added to ongoing Lamivudine therapy in Lamivudine-resistant chronic hepatitis B.
Digestive diseases and sciences - 1 Apr 2011
Wu Shuang, Fukai Kenichi, Imazeki Fumio, Arai Makoto, Kanda Tatsuo, Yonemitsu Yutaka, Yokosuka Osamu
Abstract excerpt
BACKGROUND: Although adefovir dipivoxil (ADV) has been used for antiviral treatment of lamivudine (LAM)-resistant chronic hepatitis B (CHB) patients, the long-term efficacy of this treatment is not well understood. Initial virological response (IVR) has been reported to be an important factor in relation to the development of ADV-resistance. AIMS: We therefore examined the factors associated with IVR and ADV...
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