Article
Adefovir dipivoxil for treatment of breakthrough hepatitis caused by lamivudine-resistant mutants of hepatitis B virus.
Intervirology - 1 Jan 2004
Hosaka Tetsuya, Suzuki Fumitaka, Suzuki Yoshiyuki, Saitoh Satoshi, Kobayashi Masahiro, Someya Takashi, Sezaki Hitomi, Akuta Norio, Tsubota Akihito, Arase Yasuji, Ikeda Kenji, Kumada Hiromitsu
Abstract excerpt
OBJECTIVE: Adefovir dipivoxil (ADV) is a nucleoside analogue that inhibits wild-type hepatitis B virus (HBV) and lamivudine-resistant HBV mutants in vitro and in vivo. The aim of this study was to evaluate the efficacy of ADV against lamivudine-resistant mutants and of adefovir and interferon (IF...
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