Article
The hOGG1 Ser326Cys polymorphism is not associated with sporadic Parkinson's disease.
Neuroscience letters - 12 Apr 2010
Coppedè Fabio, Ceravolo Roberto, Migheli Francesca, Fanucchi Francesca, Frosini Daniela, Siciliano Gabriele, Bonuccelli Ubaldo, Migliore Lucia
Abstract excerpt
Parkinson's disease (PD) is one of the most common neurodegenerative disorders characterized by progressive and profound loss of dopaminergic neurons in the substantia nigra (SN) resulting in resting tremor, rigidity, bradykinesia, and postural instability. The primary cause of the disease is still unknown, but mitochondrial dysfunction and oxidative stress have been implicated in the neurodegenerative process....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.