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Article

Phosphorylated peptides are naturally processed and presented by major histocompatibility complex class I molecules in vivo.

The Journal of experimental medicine - 18 Dec 2000

Zarling A L, Ficarro S B, White F M, Shabanowitz J, Hunt D F, Engelhard V H

Abstract excerpt

Posttranslational modification of peptide antigens has been shown to alter the ability of T cells to recognize major histocompatibility complex (MHC) class I-restricted peptides. However, the existence and origin of naturally processed phosphorylated peptides presented by MHC class I molecules have not been explored. By using mass spectrometry, significant numbers of naturally processed phosphorylated peptides...

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Share to Antigen Presentation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Epitopes, T-Lymphocyte

Share to Histocompatibility Antigens Class I

Share to Interferon-gamma

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Source

Open in PubMed Open full text

Identifiers

PMID: 11120772
DOI: 10.1084/jem.192.12.1755
PMCID: PMC2213507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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