Article
Association between the polymorphism of TGF-beta1 gene promoter (-509C>T) and idiopathic chronic urticaria.
Iranian journal of allergy, asthma, and immunology - 1 Sept 2006
Hosseini Farahabadi Sara, Tavakkol-Afshari Jalil, Ganjali Rashin, Rafatpanah Houshang, Ghaffari Javad, Farid-Hosseini Reza
Abstract excerpt
Idiopathic Chronic Urticaria (ICU), the most common form (70-80%) of chronic urticaria is supposed to have immune basis causes. It is speculated that the promoter polymorphism of TGF-Beta1 gene may be involved in ICU. This condition is thought to affect at least 0.1% of the population and often can be severe and difficult to treat. A total of 40 patients with ICU and 41 normal subjects were studied. DNA was...
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