Article
Auditory deficits of Kcna1 deletion are similar to those of a monaural hearing impairment.
Hearing research - 1 Mar 2015
Karcz Anita, Allen Paul D, Walton Joseph, Ison James R, Kopp-Scheinpflug Cornelia
Abstract excerpt
Kv1.1 subunits of low voltage-activated (Kv) potassium channels are encoded by the Kcna1 gene and crucially determine the synaptic integration window to control the number and temporal precision of action potentials in the auditory brainstem of mammals and birds. Prior electrophysiological studies showed that auditory signaling is compromised in monaural as well as in binaural neurons of the auditory brainstem in...
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