Article
Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration.
American journal of physiology. Cell physiology - 1 May 2007
Wang Yaohong, Tomar Alok, George Sudeep P, Khurana Seema
Abstract excerpt
While there is circumstantial evidence to suggest a requirement for phospholipase C-gamma(1) (PLC-gamma(1)) in actin reorganization and cell migration, few studies have examined the direct mechanisms that link regulators of the actin cytoskeleton with this crucial signaling molecule. This study was aimed to examine the role that villin, an epithelial cell-specific actin-binding protein, and its ligand...
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