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Article

Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis.

International journal of cancer - 1 Jul 2013

Basu Roy Upal K, Henkhaus Rebecca S, Loupakis Fotios, Cremolini Chiara, Gerner Eugene W, Ignatenko Natalia A

Abstract excerpt

Caveolin-1 is an essential component of membrane caveolae. It is an important regulator of cellular processes such as signal transduction and endocytosis. We report here, for the first time, that caveolin-1 is a target of the K-RAS oncogene in colon carcinogenesis. Caveolin-1 is induced in colon...

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Identifiers

PMID: 23280667
DOI: 10.1002/ijc.28001
PMCID: PMC3633716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23280667-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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