Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of c-Myb during Prolactin-Induced Signal Transducer and Activator of Transcription 5a Signaling in Breast Cancer Cells

26 Nov 2008

Abstract excerpt

Implicated in the pathogenesis of breast cancer, prolactin (PRL) mediates its function in part through the prolactin receptor (PRLr)-associated Janus kinase 2 (Jak2)/signal transducer and activator of transcription 5 (Stat5) signaling complex. To delineate the mechanisms of Stat5a regulation in breast cancer, transcription factor-transcription factor (TF-TF) array analysis was employed to identify associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to NF-κB Signaling Pathways
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19036881
DOI: 10.1210/en.2008-1079

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of c-Myb during Prolactin-Induced Signal Transducer and Activator of Transcription 5a Signaling in Breast Cancer CellsPMID 19036881Read ↗

Identification and Regulation of c-Myb Target Genes in MCF-7 CellsSemantic proximity Read ↗

Role of Prolactin/Prolactin Receptor Signaling in Human Breast CancerSemantic proximity Read ↗

The prolactin receptor transactivation domain is associated with steroid hormone receptor expression and malignant progression of breast cancer.Semantic proximity Read ↗

The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cellsSemantic proximity Read ↗

Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporterSemantic proximity Read ↗

Actin-binding Rho activating C-terminal like (ABRACL) transcriptionally regulated by MYB proto-oncogene like 2 (MYBL2) promotes the proliferation, invasion, migration and epithelial-mesenchymal transition of breast cancer cellsSemantic proximity Read ↗

HMGN2 inducibly binds a novel transactivation domain in nuclear PRLr to coordinate Stat5a-mediated transcription.Semantic proximity Read ↗

CPAP Is a Novel Stat5-Interacting Cofactor that Augments Stat5-Mediated Transcriptional ActivitySemantic proximity Read ↗

The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loopSemantic proximity Read ↗

Disease-Associated Mutations of the STAT5B SH2 Domain Regulate Cytokine-Driven Enhancer Function and Mammary Development.Semantic proximity Read ↗

Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.Semantic proximity Read ↗

Potential Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.