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Article

Multiple roles for the Na,K-ATPase subunits, Atp1a1 and Fxyd1, during brain ventricle development.

Developmental biology - 15 Aug 2012

Chang Jessica T, Lowery Laura Anne, Sive Hazel

Abstract excerpt

Formation of the vertebrate brain ventricles requires both production of cerebrospinal fluid (CSF), and its retention in the ventricles. The Na,K-ATPase is required for brain ventricle development, and we show here that this protein complex impacts three associated processes. The first requires both the alpha subunit (Atp1a1) and the regulatory subunit, Fxyd1, and leads to formation of a cohesive neuroepithelium,...

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Identifiers

PMID: 22683378
DOI: 10.1016/j.ydbio.2012.05.034
PMCID: PMC3402628

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