Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine.

doi:10.1002/ajmg.b.30464

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Article

Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2007

Ehringer Marissa A, Clegg Hilary V, Collins Allan C, Corley Robin P, Crowley Thomas, Hewitt John K, Hopfer Christian J, Krauter Kenneth, Lessem Jeffrey, Rhee Soo Hyun, Schlaepfer Isabel, Smolen Andrew, Stallings Michael C, Young Susan E, Zeiger Joanna S

Abstract excerpt

Nicotine addiction and alcohol dependence are highly comorbid disorders that are likely to share overlapping genetic components. We have examined two neuronal nicotinic receptor subunit genes (CHRNA4 and CHRNB2) for possible associations with nicotine and alcohol phenotypes, including measures of frequency of use and measures of initial subjective response in the period shortly after first using the drugs. The...

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Identifiers

PMID: 17226798
DOI: 10.1002/ajmg.b.30464

Genes

CHRNB2
CHRNA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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