Article
Endogenous retroviral insertion in Cryge in the mouse No3 cataract mutant.
Genomics - 1 Apr 2007
Nag Nabanita, Peterson Katherine, Wyatt Keith, Hess Sonja, Ray Sugata, Favor Jack, Bogani Debora, Lyon Mary, Wistow Graeme
Abstract excerpt
No3 (nuclear opacity 3) is a novel congenital nuclear cataract in mice. Microsatellite mapping placed the No3 locus on chromosome 1 between D1Mit480 (32cM) and D1Mit7 (41cM), a region containing seven crystallin genes; Cryba2 and the Cryga-Crygf cluster. Although polymorphic variants were observed, no candidate mutations were found for six of the genes. However, DNA walking identified a murine endogenous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
