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Article

Cat3vl and Cat3vao cataract mutations on mouse chromosome 10: phenotypic characterization, linkage studies and analysis of candidate genes.

Molecular & general genetics : MGG - 1 Dec 1997

Löster J, Immervoll T, Schmitt-John T, Graw J

Abstract excerpt

Cat3vl and Cat3vao are two allelic, dominant cataract mutations that arose independently in the F1 generation after gamma-irradiation of male mice. The cataracts are already present at birth. Examination of the eyes with a slit lamp revealed completely vacuolated lenses in Cat3vl mutants and anteriorly located opacity in Cat3vao mutants. The appearance of the opacities does not differ between the individuals or...

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PMID: 9439574
DOI: 10.1007/s004380050628

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