Article
A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.
Investigative ophthalmology & visual science - 1 Jan 2002
Graw Jochen, Neuhäuser-Klaus Angelika, Löster Jana, Favor Jack
Abstract excerpt
PURPOSE: A mouse mutant expressing a bilateral nuclear and radial cataract was found after paternal treatment with chlorambucil. The purpose of this study was to establish the linkage of the mutation to a particular chromosome to allow molecular characterization. Moreover, the mutants were examined morphologically. METHODS: Isolated lenses were photographed and histologic sections of the eye were analyzed...
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