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Article

V76D mutation in a conserved gD-crystallin region leads to dominant cataracts in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2002

Graw Jochen, Löster Jana, Soewarto Dian, Fuchs Helmut, Reis André, Wolf Eckhard, Balling Rudi, Hrabé de Angelis Martin

Abstract excerpt

During a large-scale ENU mutagenesis screen, a mouse mutant with a dominant cataract was detected and referred to as Aey4. Aim of this study was the morphological description of the mutant, the mapping of the mutation, and the characterization of the underlying molecular lesion. The slit-lamp examination revealed a strong nuclear cataract surrounded by a homogeneous milky opacity in the inner cortex. The...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12226711
DOI: 10.1007/s00335-002-3021-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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