Article
[Evaluation of MTHFR C677T gene polymorphism and homocysteine level in coronary atherosclerotic disease].
Arquivos brasileiros de endocrinologia e metabologia - 1 Dec 2006
Muniz Maria Tereza C, Siqueira Erika R F, Fonseca Rosana A, D'Almeida Vânia, Hotta Júlia K, dos Santos José E, Cavalcanti Maria do S M, Sampaio Cláudio A M
Abstract excerpt
OBJECTIVE: The aim of this study is to determine the prevalence of C677T methylenetetrahydrofolate reductase (MTHFR) polymorphism and correlate it with plasma homocysteine levels in coronary artery disease (CAD). METHODS: Ninety-three patients with documented CAD from Hospital Universitário Oswaldo Cruz (Recife, PE, Brazil) and 108 healthy controls were evaluated. Homocysteine and folate levels were determined by...
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