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Article

[Association of C677T gene polymorphisms of methylenetetrahydrofolate reductase and plasma homocysteine level with hyperlipidemia].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jul 2014

Liang Ruilian, Zhou Yuanqing, Xie Jianmin, Lv Weibiao, Kang Bin, Liang Yuquan, Chen Yinghui, Li Yunxi

Abstract excerpt

OBJECTIVE: To study the association of methylenetetrahydrofolate reductase (MTHFR) gene C677T mutation and plasma homocysteine (Hcy) levels with hyperlipidemia. METHODS: Blood samples were collected from 1591 adults for detecting MTHFR gene C677T polymorphism with polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), plasma Hcy levels with enzymatic cycling method, and blood lipid levels...

Topics

Adult
Gene Frequency
Genotype
Homocysteine
Humans
Hyperlipidemias
Methylenetetrahydrofolate Reductase (NADPH2)
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 25176095

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-25176095-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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