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Article

Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor.

Molecular and cellular biology - 1 Mar 2007

Ying Hao, Araki Osamu, Furuya Fumihiko, Kato Yasuhito, Cheng Sheue-Yann

Abstract excerpt

Thyroid hormone (T3) is critical for growth, differentiation, and maintenance of metabolic homeostasis. Mice with a knock-in mutation in the thyroid hormone receptor alpha gene (TRalpha1PV) were created previously to explore the roles of mutated TRalpha1 in vivo. TRalpha1PV is a dominant negative mutant with a frameshift mutation in the carboxyl-terminal 14 amino acids that results in the loss of T3 binding and...

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Share to Adipogenesis
Share to Lipoprotein Lipase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17220280
DOI: 10.1128/MCB.02189-06
PMCID: PMC1820484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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