Article
Physiological consequences of the TRalpha1 aporeceptor state.
Heart failure reviews - 1 Mar 2010
Mittag Jens, Wallis Karin, Vennström Björn
Abstract excerpt
Many patients have been characterized harboring a mutation in thyroid hormone receptor (TR) beta. Surprisingly none has yet been identified carrying a mutation in TRalpha1. To facilitate the identification of such patients, several animal models with a mutant TRalpha1 have been generated. While some phenotypic characteristics, such as an adult euthyroidism, are similar in the mutant mice, other aspects such as...
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