Article
The circling mouse (C57BL/6J-cir) has a 40-kilobase genomic deletion that includes the transmembrane inner ear (tmie) gene.
Comparative medicine - 1 Dec 2006
Cho Kyoung In, Suh Jun-Gyo, Lee Jeong Woong, Hong Sung Hwa, Kang Tae-Cheon, Oh Yang-Seok, Ryoo Zae Young
Abstract excerpt
The circling mouse (C57BL6-cir) shows deafness and circling behavior in homozygotes. The mutation is transmitted with 100% penetrance by an autosomal recessive gene on chromosome 9. In the present study, we characterized the circling mutation as a 40-kilobase deletion that includes the transmembrane inner ear (tmie) gene. The tmie gene was first identified because its mutation causes deafness and circling...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.