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Article

Circling behavior in the Ecl mouse is caused by lateral semicircular canal defects.

The Journal of comparative neurology - 19 Jan 2004

Cryns Kim, van Alphen Arjan M, van Spaendonck Michiel P, van de Heyning Paul H, Timmermans Jean-Pierre, de Zeeuw Chris I, van Camp Guy

Abstract excerpt

The epistatic circler mouse (Ecl mouse) is a preexisting mutant, which displays a circling phenotype and hyperactivity. It has been shown that the circling phenotype in this mutant results from a complex inheritance pattern, but the vestibular pathology has not been analyzed. The present study deals with the morphological and functional basis responsible for the circling behavior in the Ecl mouse. Morphological...

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Identifiers

PMID: 14689488
DOI: 10.1002/cne.10975

Genes

ABR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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