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Article

The impact of genotyping error on family-based analysis of quantitative traits.

European journal of human genetics : EJHG - 1 Feb 2001

Abecasis G R, Cherny S S, Cardon L R

Abstract excerpt

Errors in genotyping can substantially influence the power to detect linkage using affected sib-pairs, but it is not clear what effect such errors have on quantitative trait analyses. Here we use Monte Carlo simulation to examine the influence of genotyping error on multipoint vs two-point analys...

Topics

Alleles
Chromosome Mapping
Computer Simulation
Gene Frequency
Genetic Linkage
Genotype
Humans
Lod Score
Logistic Models
Matched-Pair Analysis
Models, Genetic
Monte Carlo Method

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nuclear Family

Quantitative Trait, Heritable

Reproducibility of Results

Source

Identifiers

PMID: 11313746
DOI: 10.1038/sj.ejhg.5200594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-11313746-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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