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Article

Accumulating quantitative trait linkage evidence across multiple datasets using the posterior probability of linkage.

Genetic epidemiology - 1 Feb 2007

Bartlett Christopher W, Vieland Veronica J

Abstract excerpt

Genome scans for complex disorders are frequently inconclusive, prompting researchers to increase sample size in an effort to obtain stronger evidence. However, increasing sample size in the presence of locus heterogeneity may actually, on average, decrease the linkage signal at a true susceptibility gene. The posterior probability of linkage, or PPL, was specifically designed to address this issue in the context...

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Source

Identifiers

PMID: 17123305
DOI: 10.1002/gepi.20193

Genes

PPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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