The lipoprotein/lipid profile is modulated by a gene-diet interaction effect between polymorphisms in the liver X receptor-alpha and dietary cholesterol intake in French-Canadians.

doi:10.1017/S0007114507201722

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Article

The lipoprotein/lipid profile is modulated by a gene-diet interaction effect between polymorphisms in the liver X receptor-alpha and dietary cholesterol intake in French-Canadians.

The British journal of nutrition - 1 Jan 2007

Robitaille Julie, Houde Alain, Lemieux Simone, Gaudet Daniel, Pérusse Louis, Vohl Marie-Claude

Abstract excerpt

Genetic and nutritional factors interact together and modulate the plasma lipid profile. We identified variations in the gene encoding the liver X receptor alpha (LXRalpha) and investigated their effects on the plasma lipoprotein/lipid profile. We also examined whether the association between cholesterol intake and plasma lipid profile was modulated by LXRalpha variants. The LXRalpha gene was sequenced in...

Topics

Adult
Age Factors
Alleles
Bayes Theorem
Cholesterol, Dietary
Cholesterol, LDL
DNA-Binding Proteins
Energy Intake
Female
France
Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterozygote

Humans

Hypercholesterolemia

Lipids

Lipoproteins

Liver

Liver X Receptors

Source

Open in PubMed

Identifiers

PMID: 17217555
DOI: 10.1017/S0007114507201722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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