Article
Dietary intake of n-6 fatty acids modulates effect of apolipoprotein A5 gene on plasma fasting triglycerides, remnant lipoprotein concentrations, and lipoprotein particle size: the Framingham Heart Study.
Circulation - 2 May 2006
Lai Chao-Qiang, Corella Dolores, Demissie Serkalem, Cupples L Adrienne, Adiconis Xian, Zhu Yueping, Parnell Laurence D, Tucker Katherine L, Ordovas Jose M
Abstract excerpt
BACKGROUND: Apolipoprotein A5 gene (APOA5) variation is associated with plasma triglycerides (TGs). However, little is known about whether dietary fat modulates this association. METHODS AND RESULTS: We investigated the interaction between APOA5 gene variation and dietary fat in determining plasma fasting TGs, remnant-like particle (RLP) concentrations, and lipoprotein particle size in 1001 men and 1147 women who...
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