Article
Complex interference in the eye developmental pathway by Drosophila NF-YA.
Genesis (New York, N.Y. : 2000) - 1 Jan 2007
Yoshioka Yasuhide, Suyari Osamu, Yamada Mikihiro, Ohno Katsuhito, Hayashi Yuko, Yamaguchi Masamitsu
Abstract excerpt
The CCAAT motif-binding factor NF-Y consists of three different subunits, NF-YA, NF-YB, and NF-YC, all of which are required for formation of the NF-Y complex and DNA-binding. NF-YA contains a DNA binding domain in its C-terminal region. We established transgenic fly lines carrying the UAS-HA-dNF-YA or UAS-dNF-YAIR and showed over-expression or knockdown with various GAL4 drivers to be lethal at various...
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