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Article

Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein.

Cell - 21 Aug 1992

Lai Z C, Rubin G M

Abstract excerpt

Loss-of-function mutations in the yan gene result in the differentiation of supernumerary photoreceptors in the Drosophila eye. The yan gene encodes a protein with an ETS DNA-binding domain that accumulates in the nuclei of undifferentiated cells during the early stages of eye development. Our data suggest that yan functions as a cell-autonomous negative regulator of photoreceptor development; in the presumptive...

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PMID: 1505027
DOI: 10.1016/0092-8674(92)90430-k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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