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Article

Actin-dependent regulation of connective tissue growth factor.

American journal of physiology. Cell physiology - 1 May 2007

Muehlich Susanne, Cicha Iwona, Garlichs Christoph D, Krueger Bettina, Posern Guido, Goppelt-Struebe Margarete

Abstract excerpt

Expression of connective tissue growth factor (CTGF) in endothelial cells is modulated by shear stress affecting the organization of the cytoskeleton. The molecular connection between alterations of actin and CTGF expression was investigated in human umbilical vein endothelial cells (HUVEC) and a microvascular endothelial cell line. Overexpression of nonpolymerizable monomeric actin R62D interfered with stress...

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Source

Identifiers

PMID: 17215322
DOI: 10.1152/ajpcell.00552.2006

Genes

SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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