Article
Polymorphism of DNA repair genes OGG1, XRCC1, XPD and ERCC6 in bladder cancer in Belarus.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Sept 2014
Ramaniuk Volha P, Nikitchenko Nataliya V, Savina Nataliya V, Kuzhir Tatyana D, Rolevich Alexander I, Krasny Sergei A, Sushinsky Vadim E, Goncharova Roza I
Abstract excerpt
CONTEXT: The study of DNA base and nucleotide excision repair gene polymorphisms in bladder cancer seems to have a predictive value because of the evident relationship between the DNA damage response induced by environmental mutagens and cancer predisposition. OBJECTIVE: The objective was to determine OGG1 Ser326Cys, XRCC1 Arg399Gln, XPD Asp312Asn, and ERCC6 Met1097Val polymorphisms in bladder cancer patients as...
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