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Article

Specific inhibition of HBV replication in vitro and in vivo with expressed long hairpin RNA.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Mar 2007

Weinberg Marc S, Ely Abdullah, Barichievy Samantha, Crowther Carol, Mufamadi Steven, Carmona Sergio, Arbuthnot Patrick

Abstract excerpt

Activating RNA interference to achieve specific gene silencing has shown promise for the development of RNA-based treatment of chronic hepatitis B virus (HBV) infection. To further this approach, we assessed the efficacy of expressed long hairpin RNAs (lhRNAs) that target the conserved HBx open r...

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Identifiers

PMID: 17213835
DOI: 10.1038/sj.mt.6300077

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17213835-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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