Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human MHC region harbors both susceptibility and protective haplotypes for coronary artery disease.

Tissue antigens - 1 Jan 2007

Palikhe A, Sinisalo J, Seppänen M, Valtonen V, Nieminen M S, Lokki M L

Abstract excerpt

Aiming to study the role of human major histocompatibility complex (MHC) region on coronary artery disease (CAD), we enrolled two separate patient materials and controls. First, heart transplantation recipients (n = 276) were divided into three subgroups according to the severity of atherosclerosis. The human leukocyte antigen (HLA)-A-B-DR haplotype and gene frequencies were compared between groups. Second,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Haplotypes
Share to Coronary Artery Disease
Share to CAD gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to LTA gene

Share to Genetic Predisposition to Disease

Share to HLA Antigens

Share to Major Histocompatibility Complex

Source

Identifiers

PMID: 17212707
DOI: 10.1111/j.1399-0039.2006.00735.x

Genes

LTA
CAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human MHC region harbors both susceptibility and protective haplotypes for coronary artery disease.PMID 17212707Read ↗

Association between HLA-DQB1 alleles and susceptibility to coronary artery disease in Southern Han Chinese.Semantic proximity Read ↗

Impact of Intercellular Adhesion Molecule-1 Genetic Polymorphisms on Coronary Artery Disease Susceptibility in Taiwanese Subjects.Semantic proximity Read ↗

Association of TLR and TREM-1 gene polymorphisms with risk of coronary artery disease in a Russian population.Semantic proximity Read ↗

Associations between the rs5498 (A > G) and rs281432 (C > G) polymorphisms of the ICAM1 gene and atherosclerotic cardiovascular disease risk, including hypercholesterolemia.Semantic proximity Read ↗

HLA-DRB1*12:02:01 plays a protective role against coronary artery disease in women of southern Han Chinese descent.Semantic proximity Read ↗

Proinflammatory HLA-DRB1*01-haplotype predisposes to ST-elevation myocardial infarction.Semantic proximity Read ↗

Associations between the ICAM1 gene polymorphisms and atherosclerotic cardiovascular disease risk, including hypercholesterolemia, in rural ThaisSemantic proximity Read ↗

ICAM-1 and MKL-1 polymorphisms impose considerable impacts on coronary heart disease occurrence.Semantic proximity Read ↗

HLA-DRB1 and HLA-DQB1 genetic polymorphisms and susceptibility to coronary atherosclerosis in a Northeast Chinese Population: A case-control study.Semantic proximity Read ↗

A single nucleotide polymorphism in the stromal cell-derived factor 1 gene is associated with coronary heart disease in Chinese patients.Semantic proximity Read ↗

IL-8 -251A/T polymorphism contributes to coronary artery disease susceptibility in a Chinese population.Semantic proximity Read ↗

Association between a genetic variant in scavenger receptor class B type 1 and its role on codon usage bias with increased risk of developing coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.