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Article

HLA-DRB1*12:02:01 plays a protective role against coronary artery disease in women of southern Han Chinese descent.

Human immunology - 1 Jan 2012

Liu Benrong, Xiong Longgen, Tian Chaowei, Zhou Qiang, Zhong Yun, Li Aiqun, Liu Shi-Ming

Abstract excerpt

The pathogenesis of coronary artery disease (CAD) is closely associated with inflammation, in which human leukocyte antigens (HLA), especially HLA-DR molecules, play important roles. However, whether various HLA-DRB1 alleles can contribute differing susceptibility to CAD has not been elucidated. In this study, we demonstrated a significantly lower frequency of HLA-DRB1*12:02:01 in the CAD group (9.82%) than in...

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Source

Identifiers

PMID: 22122841
DOI: 10.1016/j.humimm.2011.11.003

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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