IL-8 -251A/T polymorphism contributes to coronary artery disease susceptibility in a Chinese population.

doi:10.4238/gmr16018224

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IL-8 -251A/T polymorphism contributes to coronary artery disease susceptibility in a Chinese population.

Genetics and molecular research : GMR - 16 Feb 2017

Zhang R J, Li X D, Zhang S W, Li X H, Wu L

Abstract excerpt

Interleukin-8 (IL-8) is a mediator of inflammation and plays an important role in regulating immune responses. To date, several studies have tested the association between IL-8 gene polymorphisms and development of coronary artery disease (CAD), but their results have proved to be inconsistent. We conducted an investigation to assess the relationship between the IL-8 -251A/T (rs4073) sequence variant and CAD in a...

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PMID: 28218776
DOI: 10.4238/gmr16018224

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