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Article

Proinflammatory HLA-DRB1*01-haplotype predisposes to ST-elevation myocardial infarction.

Atherosclerosis - 1 Apr 2012

Paakkanen Riitta, Lokki Marja-Liisa, Seppänen Mikko, Tierala Ilkka, Nieminen Markku S, Sinisalo Juha

Abstract excerpt

BACKGROUND: Major histocompatibility complex (MHC) gene region harbours haplotypes that associate with coronary artery disease (CAD). Their role in ST-elevation infarction (STEMI) or on the inflammatory level is not known. METHODS: Four candidate MHC markers were analyzed by real-time quantitative PCR and constructed into haplotypes from patients with STEMI (n = 162), matched controls with no CAD (n = 319) and...

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PMID: 22310063
DOI: 10.1016/j.atherosclerosis.2012.01.024

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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