Association between a genetic variant in scavenger receptor class B type 1 and its role on codon usage bias with increased risk of developing coronary artery disease.

doi:10.1016/j.clinbiochem.2021.06.001

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Article

Association between a genetic variant in scavenger receptor class B type 1 and its role on codon usage bias with increased risk of developing coronary artery disease.

Clinical biochemistry - 1 Sept 2021

Sahebi Reza, Ghazizadeh Hamideh, Avan Amir, Tayefi Maryam, Saffar-Soflaei Sara, Mouhebati Mohsen, Esmaily Habibollah, Ferns Gordon A, Hashemzadeh-Chaleshtori Morteza, Ghayour-Mobarhan Majid, Farrokhi Effat

Abstract excerpt

OBJECTIVE: Coronary artery disease (CAD) as an important cause of morbidity and mortality globally. The scavenger receptor class B type 1 (SCARB1) plays an essential role in the reverse cholesterol transport. We have explored the association between a genetic variant, rs5888, in the SCARB1 gene with CAD and serum HDL-C levels. METHODS: Patients were categorized into two groups' angiogram positive (>50% coronary...

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PMID: 34097878
DOI: 10.1016/j.clinbiochem.2021.06.001

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