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Article

Age-related macular degeneration: genetics and biology coming together.

Annual review of genomics and human genetics - 1 Jan 2014

Fritsche Lars G, Fariss Robert N, Stambolian Dwight, Abecasis Gonçalo R, Curcio Christine A, Swaroop Anand

Abstract excerpt

Genetic and genomic studies have enhanced our understanding of complex neurodegenerative diseases that exert a devastating impact on individuals and society. One such disease, age-related macular degeneration (AMD), is a major cause of progressive and debilitating visual impairment. Since the pioneering discovery in 2005 of complement factor H (CFH) as a major AMD susceptibility gene, extensive investigations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24773320
DOI: 10.1146/annurev-genom-090413-025610
PMCID: PMC4217162

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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