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Article

Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2007

DeAngelis Margaret M, Ji Fei, Kim Ivana K, Adams Scott, Capone Antonio, Ott Jurg, Miller Joan W, Dryja Thaddeus P

Abstract excerpt

OBJECTIVE: To examine if the genes encoding complement factor H (CFH), apolipoprotein E (APOE), and elongation of very-long-chain fatty acids-like 4 (ELOVL4) confer risk of neovascular age-related macular degeneration (AMD) in an independent or interactive manner when controlling for smoking exposure. METHODS: We studied 103 unrelated patients with neovascular AMD who each had at least 1 sibling with normal...

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Source

Identifiers

PMID: 17210851
DOI: 10.1001/archopht.125.1.49

Genes

CFH
APOE
ELOVL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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