Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration.

Molecular vision - 17 Nov 2010

Seddon Johanna M, Reynolds Robyn, Rosner Bernard

Abstract excerpt

OBJECTIVE: A novel locus in the hepatic lipase (LIPC) gene was found to be significantly related to advanced age-related macular degeneration (AMD) in our genome-wide association study. We evaluated its association and interaction with previously identified genetic variants and modifiable factors. METHODS: Participants in the Age-Related Eye Disease Study with advanced AMD (n=545 cases) or no AMD (n=275 controls)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Demography
Share to Life Style

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lipase

Share to Lutein

Share to Macular Degeneration

Share to Multivariate Analysis

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 21139980
PMCID: PMC2994762

Genes

LIPC
CFH
CFI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration.PMID 21139980Read ↗

Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration.Semantic proximity Read ↗

Association of LIPC and advanced age-related macular degeneration.Semantic proximity Read ↗

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).Semantic proximity Read ↗

The relationship between hepatic lipase gene variant and advanced age-related macular degeneration: a meta-analysis.Semantic proximity Read ↗

CETP/LPL/LIPC gene polymorphisms and susceptibility to age-related macular degeneration.Semantic proximity Read ↗

The Association between LIPC rs493258 Polymorphism and the Susceptibility to Age-Related Macular Degeneration.Semantic proximity Read ↗

Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.Semantic proximity Read ↗

CETP Gene may be Associated with Advanced Age-Related Macular Degeneration in the Chinese Population.Semantic proximity Read ↗

[Mendelian randomization study of the relationship between high-density lipoprotein cholesterol and age-related macular degeneration].Semantic proximity Read ↗

Association of HDL-related loci with age-related macular degeneration and plasma lutein and zeaxanthin: the Alienor study.Semantic proximity Read ↗

Effect of High-Density Lipoprotein Metabolic Pathway Gene Variations and Risk Factors on Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in China.Semantic proximity Read ↗

Genetic evidence for role of carotenoids in age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.