Article
Combined effects of complement factor H genotypes, fish consumption, and inflammatory markers on long-term risk for age-related macular degeneration in a cohort.
American journal of epidemiology - 1 Mar 2009
Wang Jie Jin, Rochtchina Elena, Smith Wayne, Klein Ronald, Klein Barbara E K, Joshi Tripti, Sivakumaran Theru A, Iyengar Sudha, Mitchell Paul
Abstract excerpt
At baseline in 1992-1994, the authors assessed the combined effects of complement factor H (CFH) genotypes with smoking, fish consumption, and inflammatory markers on the risk of age-related macular degeneration (AMD) in 3,654 persons aged > or =49 years. They reexamined 75% of the survivors after 5 and 10 years, confirming incident AMD by side-by-side photographic grading. Of the 2,452 persons followed in the...
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