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Article

Forced expression of Phox2 homeodomain transcription factors induces a branchio-visceromotor axonal phenotype.

Developmental biology - 15 Mar 2007

Hirsch Marie-Rose, Glover Joel C, Dufour Héloïse D, Brunet Jean-François, Goridis Christo

Abstract excerpt

What causes motor neurons to project into the periphery is not well understood. We here show that forced expression of the homeodomain protein Phox2b, shown previously to be necessary and sufficient for branchio-visceromotor neuron development, and of its paralogue Phox2a imposes a branchiomotor-like axonal phenotype in the spinal cord. Many Phox2-transfected neurons, whose axons would normally stay within the...

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Identifiers

PMID: 17208219
DOI: 10.1016/j.ydbio.2006.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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