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Article

A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons.

Neuron - 1 Sept 2005

Lieberam Ivo, Agalliu Dritan, Nagasawa Takashi, Ericson Johan, Jessell Thomas M

Abstract excerpt

Motor neurons, alone among neurons in the vertebrate CNS, extend axons out of the neural tube to innervate peripheral targets. Two classes of motor neurons, termed vMNs and dMNs, extend axons out of the neural tube via ventral and dorsal exit points, respectively, in accord with their homeodomain...

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Source

Identifiers

PMID: 16129397
DOI: 10.1016/j.neuron.2005.08.011

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16129397-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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