Article
Rac1 activity is required for cardiac myocyte alignment in response to mechanical stress.
Biochemical and biophysical research communications - 23 Feb 2007
Yamane Masako, Matsuda Takahisa, Ito Takashi, Fujio Yasushi, Takahashi Kyoko, Azuma Junichi
Abstract excerpt
Mechanical stretch is essential for the cardiac growth. The exposure of cardiac myocytes to the mechanical stretch leads to the cell alignment in parallel to the stretch direction, determining the cell polarity, though it remains to be addressed how mechanical stretch regulates cell orientation....
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