Article
Mechanically induced orientation of adult rat cardiac myocytes in vitro.
In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Sept 1990
Samuel J L, Vandenburgh H H
Abstract excerpt
A population of freshly isolated adult rat cardiac myocytes is spatially oriented using a computerized mechanical cell stimulator device for tissue cultured cells. A continuous unidirectional stretch of the substratum at 60 to 400 micron/min for 120 to 30 min, respectively, during the cell attachment period in serum-free medium induces a significant three-fold increase in the number of rod-shaped myocytes...
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