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[Combined effect of recombinant mutant human TRAIL and daunorubicin in inducing apoptosis of leukemia cell and its mechanism].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2006

Zhang Xue-Jun, Wen Li, Wang Fu-Xu, Luo Jian-Min, Pan Ling, Liu Xiao-Jun, DU Xing-Yan, Dong Zuo-Ren, Yang Shi-Fang

Abstract excerpt

The aim of study was to investigate the combined effect of recombinant mutant human TRAIL (rmhTRAIL) with daunorubicin (DNR) or alone on K562 and U937 leukemia cell lines and its mechanism. The fibroblasts (MRC-5) of normal-human embryonic lung were used as control cells. After being treated with rmhTRAIL and DNR or only with rmTRAIL, the cytotoxic effect and the apoptosis rate in K562, U937 cells were measured...

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Identifiers

PMID: 17204177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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