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Article

TRAIL as a target in anti-cancer therapy.

Cancer letters - 18 Nov 2009

Wu Gen Sheng

Abstract excerpt

The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate apoptosis through the activation of their death receptors. The ability of TRAIL to selectively induce apoptosis of transformed or tumor cells but not normal cells promote...

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Source

Identifiers

PMID: 19299078
DOI: 10.1016/j.canlet.2009.02.029

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19299078-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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TRAIL as a target in anti-cancer therapy.PMID 19299078Read ↗

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State of Art and Recent Developments of Anti-Cancer Strategies Based on TRAILSemantic proximity Read ↗

[TNF-related apoptosis-inducing ligand signaling pathway and hematopoietic malignancies].Semantic proximity Read ↗

Caspase-8 regulation of TRAIL-mediated cell death.Semantic proximity Read ↗

Apoptosis-Inducing TNF Superfamily Ligands for Cancer TherapySemantic proximity Read ↗

Mechanisms of resistance to TRAIL-induced apoptosis in cancer.Semantic proximity Read ↗

Mutations Enhancing Selectivity of Antitumor Cytokine TRAIL to DR5 Receptor Increase Its Cytotoxicity against Tumor Cells.Semantic proximity Read ↗

TRAIL Modulates the Immune System and Protects against the Development of DiabetesSemantic proximity Read ↗

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants.Semantic proximity Read ↗

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